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Ozempic is great for weight loss -- but losing muscle is a side effect to watch out for | Vox

www.vox.com

Date posted: January 27, 2026 at 1:23pm

The GLP-1 drugs -- Zepbound, Wegovy, Mounjaro, Ozempic. -- can lead to people feeling weaker and having less energy. But a protein-rich healthy diet and weight training can help.

Expanded Summary

Ozempic and other GLP-1 receptor agonists, such as Zepbound, Wegovy, and Mounjaro, have gained popularity for their effectiveness in promoting weight loss. However, while these medications can help shed excess pounds, they may also result in unintended consequences, particularly the loss of muscle mass. This article delves into the potential side effects of using Ozempic for weight loss, emphasizing the importance of maintaining a balanced, protein-rich diet and incorporating regular weight training exercises to counteract muscle loss. By understanding these dynamics, users can navigate their weight loss journey more effectively and healthily.

What you’ll learn

The potential side effects of Ozempic, including muscle loss and decreased energy levels.

How a protein-rich diet can help mitigate the negative effects of weight loss medications.

Effective weight training strategies to preserve muscle mass while losing weight.

Why this matters

Understanding the side effects of weight loss medications like Ozempic is crucial for anyone looking to improve their health. While these drugs can be effective in reducing body weight, the risk of muscle loss can compromise overall strength and energy. By adopting a holistic approach that includes proper nutrition and exercise, individuals can achieve sustainable weight loss without sacrificing their physical well-being.

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